Kleenex Anti-Viral Facial Tissues are the only facial tissue that can kill 99.9% of cold and flu viruses*. Whether it's for your home, office, or classroom, you'll have plenty for everyone with 12 cube boxes of 55 Kleenex Anti-Viral Facial Tissues. Kleenex Anti-Viral Disposable Facial Tissues have a specially treated middle layer that wipes out cold and flu viruses in the tissue. When moisture hits the middle layer, the tissue will kill 99.9% of the viruses in the tissue. Plus, you can find a Kleenex tissue box that fits your home because each tissue box is available in various colors and designs. Packaging may vary. Kleenex Tissues were first introduced in 1924. Although it was originally marketed as a cold cream remover, people used the tissue in many other ways, especially as a disposable handkerchief. In 1930, advertising was changed to reflect this usage, and today more people buy Kleenex Facial Tissues than any other brand. Kimberly-Clark also has one of the most progressive fiber procurement policies in the tissue industry. We support forestry practices that help conserve valuable forestlands, respect fundamental human rights, and ensure both a thriving ecosystem and a sustainable source of wood fiber for the future.